The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization

Unlike other kinesins, members of the kinesin-13 subfamily do not move directionally along microtubules but, instead, depolymerize them. To understand how kinesins with structurally similar motor domains can have such dissimilar functions, we elucidated the ATP turnover cycle of the kinesin-13, MCAK...

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Detalles Bibliográficos
Autores principales: Friel, Claire T, Howard, Jonathon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209780/
https://www.ncbi.nlm.nih.gov/pubmed/21873978
http://dx.doi.org/10.1038/emboj.2011.290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209780/
https://www.ncbi.nlm.nih.gov/pubmed/21873978
http://dx.doi.org/10.1038/emboj.2011.290

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