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The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization
Unlike other kinesins, members of the kinesin-13 subfamily do not move directionally along microtubules but, instead, depolymerize them. To understand how kinesins with structurally similar motor domains can have such dissimilar functions, we elucidated the ATP turnover cycle of the kinesin-13, MCAK...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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European Molecular Biology Organization
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209780/ https://www.ncbi.nlm.nih.gov/pubmed/21873978 http://dx.doi.org/10.1038/emboj.2011.290 |