Regulation of the HIV-1 promoter by HIF-1α and Vpr proteins

We previously demonstrated the ability of HIV-1 Vpr protein to activate the oxidative stress pathway, thus leading to the induction of the hypoxia inducible factor 1 alpha (HIF-1α). Therefore, we sought to examine the interplay between the two proteins and the impact of HIF-1α activation on HIV-1 tr...

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Detalles Bibliográficos
Autores principales: Deshmane, Satish L, Amini, Shohreh, Sen, Satarupa, Khalili, Kamel, Sawaya, Bassel E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210103/
https://www.ncbi.nlm.nih.gov/pubmed/22023789
http://dx.doi.org/10.1186/1743-422X-8-477

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