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Flexible catalytic site conformations implicated in modulation of HIV-1 protease autoprocessing reactions

BACKGROUND: The HIV-1 protease is initially synthesized as part of the Gag-Pol polyprotein in the infected cell. Protease autoprocessing, by which the protease domain embedded in the precursor catalyzes essential cleavage reactions, leads to liberation of the free mature protease at the late stage o...

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Detalles Bibliográficos
Autores principales:	Huang, Liangqun, Li, Yanfei, Chen, Chaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210109/ https://www.ncbi.nlm.nih.gov/pubmed/21985091 http://dx.doi.org/10.1186/1742-4690-8-79

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