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Rosiglitazone-Induced Mitochondrial Biogenesis in White Adipose Tissue Is Independent of Peroxisome Proliferator-Activated Receptor γ Coactivator-1α

BACKGROUND: Thiazolidinediones, a family of insulin-sensitizing drugs commonly used to treat type 2 diabetes, are thought to exert their effects in part by promoting mitochondrial biogenesis in white adipose tissue through the transcriptional coactivator PGC-1α (Peroxisome Proliferator-Activated Rec...

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Detalles Bibliográficos
Autores principales: Pardo, Rosario, Enguix, Natàlia, Lasheras, Jaime, Feliu, Juan E., Kralli, Anastasia, Villena, Josep A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210129/
https://www.ncbi.nlm.nih.gov/pubmed/22087241
http://dx.doi.org/10.1371/journal.pone.0026989

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