The PNPLA3 rs738409 148M/M Genotype Is a Risk Factor for Liver Cancer in Alcoholic Cirrhosis but Shows No or Weak Association in Hepatitis C Cirrhosis

BACKGROUND: An isoleucine>methionine mutation at position 148 in the PNPLA3 gene (p.I148M, rs738409) has recently been identified as a susceptibility factor for liver damage in steatohepatitis. Here, we studied whether the PNPLA3 rs738409 polymorphism also affects predisposition to hepatocellular...

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Detalles Bibliográficos
Autores principales: Nischalke, Hans Dieter, Berger, Cordula, Luda, Carolin, Berg, Thomas, Müller, Tobias, Grünhage, Frank, Lammert, Frank, Coenen, Martin, Krämer, Benjamin, Körner, Christian, Vidovic, Natascha, Oldenburg, Johannes, Nattermann, Jacob, Sauerbruch, Tilman, Spengler, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210131/
https://www.ncbi.nlm.nih.gov/pubmed/22087248
http://dx.doi.org/10.1371/journal.pone.0027087

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