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Protein Characterization of a Candidate Mechanism SNP for Crohn's Disease: The Macrophage Stimulating Protein R689C Substitution

High throughput genome wide associations studies (GWAS) are now identifying a large number of genome loci related to risk of common human disease. Each such locus presents a challenge in identifying the relevant underlying mechanism. Here we report the experimental characterization of a proposed cau...

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Detalles Bibliográficos
Autores principales:	Gorlatova, Natalia, Chao, Kinlin, Pal, Lipika R., Araj, Rawan Hanna, Galkin, Andrey, Turko, Illarion, Moult, John, Herzberg, Osnat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210151/ https://www.ncbi.nlm.nih.gov/pubmed/22087277 http://dx.doi.org/10.1371/journal.pone.0027269

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