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The Proteasome Inhibitor Bortezomib Enhances ATRA-Induced Differentiation of Neuroblastoma Cells via the JNK Mitogen-Activated Protein Kinase Pathway

Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. Differentiated human NBs are associated with better outcome and lower stage; induction of differentiation is considered to be therapeutically advantageous. All-trans retinoic acid (ATRA) has been shown to induce the differe...

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Detalles Bibliográficos
Autores principales: Luo, Peihua, Lin, Meili, Li, Lin, Yang, Bo, He, Qiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210155/
https://www.ncbi.nlm.nih.gov/pubmed/22087283
http://dx.doi.org/10.1371/journal.pone.0027298