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Ku70 Alleviates Neurodegeneration in Drosophila Models of Huntington's Disease

DNA damage accumulates in genome DNA during the long life of neurons, thus DNA damage repair is indispensable to keep normal functions of neurons. We previously reported that Ku70, a critical molecule for DNA double strand break (DSB) repair, is involved in the pathology of Huntington's disease...

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Detalles Bibliográficos
Autores principales:	Tamura, Takuya, Sone, Masaki, Iwatsubo, Takeshi, Tagawa, Kazuhiko, Wanker, Erich E., Okazawa, Hitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210167/ https://www.ncbi.nlm.nih.gov/pubmed/22096569 http://dx.doi.org/10.1371/journal.pone.0027408

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