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Changes in Astrocyte Shape Induced by Sublytic Concentrations of the Cholesterol-Dependent Cytolysin Pneumolysin Still Require Pore-Forming Capacity

Streptococcus pneumoniae is a common pathogen that causes various infections, such as sepsis and meningitis. A major pathogenic factor of S. pneumoniae is the cholesterol-dependent cytolysin, pneumolysin. It produces cell lysis at high concentrations and apoptosis at lower concentrations. We have sh...

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Detalles Bibliográficos
Autores principales: Förtsch, Christina, Hupp, Sabrina, Ma, Jiangtao, Mitchell, Timothy J., Maier, Elke, Benz, Roland, Iliev, Asparouh I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210454/
https://www.ncbi.nlm.nih.gov/pubmed/22069689
http://dx.doi.org/10.3390/toxins3010043