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A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development
The phosphatidylinositol 3-kinase (PI3K) signaling pathway is a conserved signal transduction cascade that is fundamental for the correct development of the nervous system. The major negative regulator of PI3K signaling is the lipid phosphatase DAF-18/PTEN, which can modulate PI3K pathway activity d...
Autores principales: | Christensen, Ryan, de la Torre-Ubieta, Luis, Bonni, Azad, Colón-Ramos, Daniel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Company of Biologists
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210501/ https://www.ncbi.nlm.nih.gov/pubmed/22069193 http://dx.doi.org/10.1242/dev.069062 |
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