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The Mechanism of Formation of N-Formylkynurenine by Heme Dioxygenases

[Image: see text] Heme dioxygenases catalyze the oxidation of l-tryptophan to N-formylkynurenine (NFK), the first and rate-limiting step in tryptophan catabolism. Although recent progress has been made on early stages in the mechanism, there is currently no experimental data on the mechanism of prod...

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Detalles Bibliográficos
Autores principales: Basran, Jaswir, Efimov, Igor, Chauhan, Nishma, Thackray, Sarah J., Krupa, James L., Eaton, Graham, Griffith, Gerry A., Mowat, Christopher G., Handa, Sandeep, Raven, Emma Lloyd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210546/
https://www.ncbi.nlm.nih.gov/pubmed/21892828
http://dx.doi.org/10.1021/ja207066z

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