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3D-QSAR Studies on Thiazolidin-4-one S1P(1) Receptor Agonists by CoMFA and CoMSIA

Selective S1P(1) receptor agonists have therapeutic potential to treat a variety of immune-mediated diseases. A series of 2-imino-thiazolidin-4-one derivatives displaying potent S1P(1) receptor agonistic activity were selected to establish 3D-QSAR models using CoMFA and CoMSIA methods. Internal and...

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Detalles Bibliográficos
Autores principales:	Qian, Chuiwen, Zheng, Junxia, Xiao, Gaokeng, Guo, Jialiang, Yang, Zhaoqi, Huang, Li, Chao, Wei, Rao, Longyi, Sun, Pinghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210992/ https://www.ncbi.nlm.nih.gov/pubmed/22072901 http://dx.doi.org/10.3390/ijms12106502

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