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Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies

Co(II), Cu(II), Zn(II) and Fe(III) complexes of diisopropylthiourea have been synthesized and characterized by elemental analyses, molar conductivity, magnetic susceptibility, FTIR and electronic spectroscopy. The compounds are non-electrolytes in solution and spectroscopic data of the complexes are...

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Detalles Bibliográficos
Autores principales: Ajibade, Peter A., Zulu, Nonkululeko H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211032/
https://www.ncbi.nlm.nih.gov/pubmed/22072941
http://dx.doi.org/10.3390/ijms12107186
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author Ajibade, Peter A.
Zulu, Nonkululeko H.
author_facet Ajibade, Peter A.
Zulu, Nonkululeko H.
author_sort Ajibade, Peter A.
collection PubMed
description Co(II), Cu(II), Zn(II) and Fe(III) complexes of diisopropylthiourea have been synthesized and characterized by elemental analyses, molar conductivity, magnetic susceptibility, FTIR and electronic spectroscopy. The compounds are non-electrolytes in solution and spectroscopic data of the complexes are consistent with 4-coordinate geometry for the metal(II) complexes and six coordinate octahedral for Fe(III) complex. The complexes were screened for their antibacterial activities against six bacteria: Escherichia coli, Pseudomonas auriginosa, Klebsiella pneumoniae, Bacillus cereus, Staphylococcus aureus and Bacillus pumilus. The complexes showed varied antibacterial activities and their minimum inhibitory concentrations (MICs) were determined.
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spelling pubmed-32110322011-11-09 Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies Ajibade, Peter A. Zulu, Nonkululeko H. Int J Mol Sci Article Co(II), Cu(II), Zn(II) and Fe(III) complexes of diisopropylthiourea have been synthesized and characterized by elemental analyses, molar conductivity, magnetic susceptibility, FTIR and electronic spectroscopy. The compounds are non-electrolytes in solution and spectroscopic data of the complexes are consistent with 4-coordinate geometry for the metal(II) complexes and six coordinate octahedral for Fe(III) complex. The complexes were screened for their antibacterial activities against six bacteria: Escherichia coli, Pseudomonas auriginosa, Klebsiella pneumoniae, Bacillus cereus, Staphylococcus aureus and Bacillus pumilus. The complexes showed varied antibacterial activities and their minimum inhibitory concentrations (MICs) were determined. Molecular Diversity Preservation International (MDPI) 2011-10-21 /pmc/articles/PMC3211032/ /pubmed/22072941 http://dx.doi.org/10.3390/ijms12107186 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Ajibade, Peter A.
Zulu, Nonkululeko H.
Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies
title Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies
title_full Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies
title_fullStr Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies
title_full_unstemmed Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies
title_short Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies
title_sort metal complexes of diisopropylthiourea: synthesis, characterization and antibacterial studies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211032/
https://www.ncbi.nlm.nih.gov/pubmed/22072941
http://dx.doi.org/10.3390/ijms12107186
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