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Synthesis of macrocyclic natural products by catalyst-controlled stereoselective ring-closing metathesis
Many biologically active macrocycles contain a C–C double bond through which various other derivatives are prepared; the stereochemical identity of the alkene or the resulting moieties can be critical to the beneficial properties of such molecules. Catalytic ring-closing metathesis (RCM) is a widely...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211109/ https://www.ncbi.nlm.nih.gov/pubmed/22051677 http://dx.doi.org/10.1038/nature10563 |