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tert-Butyl N-((1S)-2-hy­droxy-1-{N′-[(E)-2-hy­droxy-4-meth­oxy­benzyl­idene]hydrazinecarbon­yl}eth­yl)carbamate

The mol­ecule of the title compound, C(16)H(23)N(3)O(6), is twisted about the chiral C atom with the dihedral angle formed between the amide residues being 76.9 (3)°. Overall, the mol­ecule is curved with the terminal organic groups lying to the same side. The conformation about the imine bond [1.29...

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Autores principales: Wardell, James L., de Souza, Marcus V. N., Pinheiro, Alessandra C., Tiekink, Edward R. T., Wardell, Solange M. S. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212283/
https://www.ncbi.nlm.nih.gov/pubmed/22090940
http://dx.doi.org/10.1107/S1600536811025293
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author Wardell, James L.
de Souza, Marcus V. N.
Pinheiro, Alessandra C.
Tiekink, Edward R. T.
Wardell, Solange M. S. V.
author_facet Wardell, James L.
de Souza, Marcus V. N.
Pinheiro, Alessandra C.
Tiekink, Edward R. T.
Wardell, Solange M. S. V.
author_sort Wardell, James L.
collection PubMed
description The mol­ecule of the title compound, C(16)H(23)N(3)O(6), is twisted about the chiral C atom with the dihedral angle formed between the amide residues being 76.9 (3)°. Overall, the mol­ecule is curved with the terminal organic groups lying to the same side. The conformation about the imine bond [1.291 (5) Å] is E and an intra­molecular O—H⋯N hydrogen bond generates an S(6) ring. In the crystal, O—H⋯O and N—H⋯O hydrogen bonds involving the hy­droxy, amine and carbonyl groups lead to the formation of supra­molecular layers, which stack along the c-axis direction.
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spelling pubmed-32122832011-11-16 tert-Butyl N-((1S)-2-hy­droxy-1-{N′-[(E)-2-hy­droxy-4-meth­oxy­benzyl­idene]hydrazinecarbon­yl}eth­yl)carbamate Wardell, James L. de Souza, Marcus V. N. Pinheiro, Alessandra C. Tiekink, Edward R. T. Wardell, Solange M. S. V. Acta Crystallogr Sect E Struct Rep Online Organic Papers The mol­ecule of the title compound, C(16)H(23)N(3)O(6), is twisted about the chiral C atom with the dihedral angle formed between the amide residues being 76.9 (3)°. Overall, the mol­ecule is curved with the terminal organic groups lying to the same side. The conformation about the imine bond [1.291 (5) Å] is E and an intra­molecular O—H⋯N hydrogen bond generates an S(6) ring. In the crystal, O—H⋯O and N—H⋯O hydrogen bonds involving the hy­droxy, amine and carbonyl groups lead to the formation of supra­molecular layers, which stack along the c-axis direction. International Union of Crystallography 2011-07-02 /pmc/articles/PMC3212283/ /pubmed/22090940 http://dx.doi.org/10.1107/S1600536811025293 Text en © Wardell et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wardell, James L.
de Souza, Marcus V. N.
Pinheiro, Alessandra C.
Tiekink, Edward R. T.
Wardell, Solange M. S. V.
tert-Butyl N-((1S)-2-hy­droxy-1-{N′-[(E)-2-hy­droxy-4-meth­oxy­benzyl­idene]hydrazinecarbon­yl}eth­yl)carbamate
title tert-Butyl N-((1S)-2-hy­droxy-1-{N′-[(E)-2-hy­droxy-4-meth­oxy­benzyl­idene]hydrazinecarbon­yl}eth­yl)carbamate
title_full tert-Butyl N-((1S)-2-hy­droxy-1-{N′-[(E)-2-hy­droxy-4-meth­oxy­benzyl­idene]hydrazinecarbon­yl}eth­yl)carbamate
title_fullStr tert-Butyl N-((1S)-2-hy­droxy-1-{N′-[(E)-2-hy­droxy-4-meth­oxy­benzyl­idene]hydrazinecarbon­yl}eth­yl)carbamate
title_full_unstemmed tert-Butyl N-((1S)-2-hy­droxy-1-{N′-[(E)-2-hy­droxy-4-meth­oxy­benzyl­idene]hydrazinecarbon­yl}eth­yl)carbamate
title_short tert-Butyl N-((1S)-2-hy­droxy-1-{N′-[(E)-2-hy­droxy-4-meth­oxy­benzyl­idene]hydrazinecarbon­yl}eth­yl)carbamate
title_sort tert-butyl n-((1s)-2-hy­droxy-1-{n′-[(e)-2-hy­droxy-4-meth­oxy­benzyl­idene]hydrazinecarbon­yl}eth­yl)carbamate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212283/
https://www.ncbi.nlm.nih.gov/pubmed/22090940
http://dx.doi.org/10.1107/S1600536811025293
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