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tert-Butyl N-((1S)-2-hydroxy-1-{N′-[(E)-2-hydroxy-4-methoxybenzylidene]hydrazinecarbonyl}ethyl)carbamate
The molecule of the title compound, C(16)H(23)N(3)O(6), is twisted about the chiral C atom with the dihedral angle formed between the amide residues being 76.9 (3)°. Overall, the molecule is curved with the terminal organic groups lying to the same side. The conformation about the imine bond [1.29...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212283/ https://www.ncbi.nlm.nih.gov/pubmed/22090940 http://dx.doi.org/10.1107/S1600536811025293 |
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author | Wardell, James L. de Souza, Marcus V. N. Pinheiro, Alessandra C. Tiekink, Edward R. T. Wardell, Solange M. S. V. |
author_facet | Wardell, James L. de Souza, Marcus V. N. Pinheiro, Alessandra C. Tiekink, Edward R. T. Wardell, Solange M. S. V. |
author_sort | Wardell, James L. |
collection | PubMed |
description | The molecule of the title compound, C(16)H(23)N(3)O(6), is twisted about the chiral C atom with the dihedral angle formed between the amide residues being 76.9 (3)°. Overall, the molecule is curved with the terminal organic groups lying to the same side. The conformation about the imine bond [1.291 (5) Å] is E and an intramolecular O—H⋯N hydrogen bond generates an S(6) ring. In the crystal, O—H⋯O and N—H⋯O hydrogen bonds involving the hydroxy, amine and carbonyl groups lead to the formation of supramolecular layers, which stack along the c-axis direction. |
format | Online Article Text |
id | pubmed-3212283 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-32122832011-11-16 tert-Butyl N-((1S)-2-hydroxy-1-{N′-[(E)-2-hydroxy-4-methoxybenzylidene]hydrazinecarbonyl}ethyl)carbamate Wardell, James L. de Souza, Marcus V. N. Pinheiro, Alessandra C. Tiekink, Edward R. T. Wardell, Solange M. S. V. Acta Crystallogr Sect E Struct Rep Online Organic Papers The molecule of the title compound, C(16)H(23)N(3)O(6), is twisted about the chiral C atom with the dihedral angle formed between the amide residues being 76.9 (3)°. Overall, the molecule is curved with the terminal organic groups lying to the same side. The conformation about the imine bond [1.291 (5) Å] is E and an intramolecular O—H⋯N hydrogen bond generates an S(6) ring. In the crystal, O—H⋯O and N—H⋯O hydrogen bonds involving the hydroxy, amine and carbonyl groups lead to the formation of supramolecular layers, which stack along the c-axis direction. International Union of Crystallography 2011-07-02 /pmc/articles/PMC3212283/ /pubmed/22090940 http://dx.doi.org/10.1107/S1600536811025293 Text en © Wardell et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Wardell, James L. de Souza, Marcus V. N. Pinheiro, Alessandra C. Tiekink, Edward R. T. Wardell, Solange M. S. V. tert-Butyl N-((1S)-2-hydroxy-1-{N′-[(E)-2-hydroxy-4-methoxybenzylidene]hydrazinecarbonyl}ethyl)carbamate |
title |
tert-Butyl N-((1S)-2-hydroxy-1-{N′-[(E)-2-hydroxy-4-methoxybenzylidene]hydrazinecarbonyl}ethyl)carbamate |
title_full |
tert-Butyl N-((1S)-2-hydroxy-1-{N′-[(E)-2-hydroxy-4-methoxybenzylidene]hydrazinecarbonyl}ethyl)carbamate |
title_fullStr |
tert-Butyl N-((1S)-2-hydroxy-1-{N′-[(E)-2-hydroxy-4-methoxybenzylidene]hydrazinecarbonyl}ethyl)carbamate |
title_full_unstemmed |
tert-Butyl N-((1S)-2-hydroxy-1-{N′-[(E)-2-hydroxy-4-methoxybenzylidene]hydrazinecarbonyl}ethyl)carbamate |
title_short |
tert-Butyl N-((1S)-2-hydroxy-1-{N′-[(E)-2-hydroxy-4-methoxybenzylidene]hydrazinecarbonyl}ethyl)carbamate |
title_sort | tert-butyl n-((1s)-2-hydroxy-1-{n′-[(e)-2-hydroxy-4-methoxybenzylidene]hydrazinecarbonyl}ethyl)carbamate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212283/ https://www.ncbi.nlm.nih.gov/pubmed/22090940 http://dx.doi.org/10.1107/S1600536811025293 |
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