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Toll-Like Receptors 2 and 4 Regulate the Frequency of IFNγ-Producing CD4(+) T-Cells during Pulmonary Infection with Chlamydia pneumoniae

TLR2 and TLR4 are crucial for recognition of Chlamydia pneumoniae in vivo, since infected TLR2/4 double-deficient mice are unable to control the infection as evidenced by severe loss of body weight and progressive lethal pneumonia. Unexpectedly, these mice display higher pulmonary levels of the prot...

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Detalles Bibliográficos
Autores principales:	Wantia, Nina, Rodriguez, Nuria, Cirl, Christine, Ertl, Tanja, Dürr, Susanne, Layland, Laura E., Wagner, Hermann, Miethke, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212512/ https://www.ncbi.nlm.nih.gov/pubmed/22096480 http://dx.doi.org/10.1371/journal.pone.0026101

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