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Suppression of Expression of Heat Shock Protein 70 by Gefitinib and Its Contribution to Pulmonary Fibrosis

Drug-induced interstitial lung disease (ILD), particularly pulmonary fibrosis, is of serious clinical concern. Gefitinib, a tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR), is beneficial as a drug for treating non-small cell lung cancer; however, this drug induces ILD and th...

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Detalles Bibliográficos
Autores principales:	Namba, Takushi, Tanaka, Ken-Ichiro, Hoshino, Tatsuya, Azuma, Arata, Mizushima, Tohru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212557/ https://www.ncbi.nlm.nih.gov/pubmed/22096546 http://dx.doi.org/10.1371/journal.pone.0027296

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