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Characterization of the Response of Primary Cells Relevant to Dialysis-Related Amyloidosis to β(2)-Microglobulin Monomer and Fibrils

The formation of insoluble amyloid fibrils is associated with an array of devastating human diseases. Dialysis-related amyloidosis (DRA) is a severe complication of hemodialysis that results in the progressive destruction of the bones and joints. Elevated concentrations of β(2)-microglobulin (β(2)m)...

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Detalles Bibliográficos
Autores principales: Porter, Morwenna Y., Routledge, Katy E., Radford, Sheena E., Hewitt, Eric W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212568/
https://www.ncbi.nlm.nih.gov/pubmed/22096558
http://dx.doi.org/10.1371/journal.pone.0027353