Defects in the Medial Entorhinal Cortex and Dentate Gyrus in the Mouse Model of Sanfilippo Syndrome Type B

Sanfilippo syndrome type B (MPS IIIB) is characterized by profound mental retardation in childhood, dementia and death in late adolescence; it is caused by deficiency of α-N-acetylglucosaminidase and resulting lysosomal storage of heparan sulfate. A mouse model, generated by homologous recombination...

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Detalles Bibliográficos
Autores principales: Ohmi, Kazuhiro, Zhao, Hui-Zhi, Neufeld, Elizabeth F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212581/
https://www.ncbi.nlm.nih.gov/pubmed/22096577
http://dx.doi.org/10.1371/journal.pone.0027461

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