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Therapeutic siRNA silencing in inflammatory monocytes

Inflammatory monocytes -- but not the non-inflammatory subset -- depend on the chemokine receptor CCR2 for distribution to injured tissue and stimulate disease progression. Precise therapeutic targeting of this inflammatory monocyte subset could spare innate immunity's essential functions for m...

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Detalles Bibliográficos
Autores principales:	Leuschner, Florian, Dutta, Partha, Gorbatov, Rostic, Novobrantseva, Tatiana I., Sullivan, Jessica, Courties, Gabriel, Lee, Kang Mi, Kim, James I., Markmann, James F., Marinelli, Brett, Panizzi, Peter, Lee, Won Woo, Iwamoto, Yoshiko, Milstein, Stuart, Epstein-Barash, Hila, Cantley, William, Wong, Jamie, Cortez-Retamozo, Virna, Newton, Andita, Love, Kevin, Libby, Peter, Pittet, Mikael J., Swirski, Filip K., Koteliansky, Victor, Langer, Robert, Weissleder, Ralph, Anderson, Daniel G., Nahrendorf, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212614/ https://www.ncbi.nlm.nih.gov/pubmed/21983520 http://dx.doi.org/10.1038/nbt.1989

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