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Leoligin, the major lignan from Edelweiss, activates cholesteryl ester transfer protein
OBJECTIVE: Cholesteryl ester transfer protein (CETP) plays a central role in the metabolism of high-density lipoprotein particles. Therefore, we searched for new drugs that bind to CETP and modulate its activity. METHODS: A preliminary pharmacophore-based parallel screening approach indicated that l...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212649/ https://www.ncbi.nlm.nih.gov/pubmed/21820657 http://dx.doi.org/10.1016/j.atherosclerosis.2011.07.023 |