Non-Viral Causes of Hepatocellular Carcinoma

INTRODUCTION: Hepatocellular carcinoma (HCC) is a major cause of cancer worldwide. The vast majority of cases occur in individuals with a chronic HBV or HCV infection. In addition, a number of metabolic diseases of the liver are associated with the development of HCC. PATHOPHYSIOLOGIC MECHANISMS: Th...

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Detalles Bibliográficos
Autores principales: Van Thiel, David H., Ramadori, Guiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212675/
https://www.ncbi.nlm.nih.gov/pubmed/20820946
http://dx.doi.org/10.1007/s12029-010-9195-3
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author Van Thiel, David H.
Ramadori, Guiliano
author_facet Van Thiel, David H.
Ramadori, Guiliano
author_sort Van Thiel, David H.
collection PubMed
description INTRODUCTION: Hepatocellular carcinoma (HCC) is a major cause of cancer worldwide. The vast majority of cases occur in individuals with a chronic HBV or HCV infection. In addition, a number of metabolic diseases of the liver are associated with the development of HCC. PATHOPHYSIOLOGIC MECHANISMS: The mechanisms responsible for the progression of the metabolic liver disease and HCC differ from those associated with viral liver disease. CONCLUSIONS: The purpose of this report is to describe the mechanisms responsible for the disease progression and HCC in case of metabolic liver disease. A secondary goal is to identify the frequency of HCC development in the disorders described.
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spelling pubmed-32126752011-11-28 Non-Viral Causes of Hepatocellular Carcinoma Van Thiel, David H. Ramadori, Guiliano J Gastrointest Cancer Review Article INTRODUCTION: Hepatocellular carcinoma (HCC) is a major cause of cancer worldwide. The vast majority of cases occur in individuals with a chronic HBV or HCV infection. In addition, a number of metabolic diseases of the liver are associated with the development of HCC. PATHOPHYSIOLOGIC MECHANISMS: The mechanisms responsible for the progression of the metabolic liver disease and HCC differ from those associated with viral liver disease. CONCLUSIONS: The purpose of this report is to describe the mechanisms responsible for the disease progression and HCC in case of metabolic liver disease. A secondary goal is to identify the frequency of HCC development in the disorders described. Springer US 2010-09-07 2011 /pmc/articles/PMC3212675/ /pubmed/20820946 http://dx.doi.org/10.1007/s12029-010-9195-3 Text en © The Author(s) 2010 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Review Article
Van Thiel, David H.
Ramadori, Guiliano
Non-Viral Causes of Hepatocellular Carcinoma
title Non-Viral Causes of Hepatocellular Carcinoma
title_full Non-Viral Causes of Hepatocellular Carcinoma
title_fullStr Non-Viral Causes of Hepatocellular Carcinoma
title_full_unstemmed Non-Viral Causes of Hepatocellular Carcinoma
title_short Non-Viral Causes of Hepatocellular Carcinoma
title_sort non-viral causes of hepatocellular carcinoma
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212675/
https://www.ncbi.nlm.nih.gov/pubmed/20820946
http://dx.doi.org/10.1007/s12029-010-9195-3
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