Improvement of Sodium Status to Optimize the Efficacy of Renin-Angiotensin System Blockade

Blockade of the renin-angiotensin-aldosterone system (RAAS) offers superior renoprotection in the treatment of patients with hypertension, but the efficacy of RAAS inhibition strongly depends on sodium status, presumably in relation to extracellular volume status. Because assessing volume status by...

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Detalles Bibliográficos
Autores principales: Laverman, Gozewijn D., Navis, Gerjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Current Science Inc. 2011
Materias:
Invited Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212696/
https://www.ncbi.nlm.nih.gov/pubmed/21964882
http://dx.doi.org/10.1007/s11906-011-0234-7
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author Laverman, Gozewijn D.
Navis, Gerjan
author_facet Laverman, Gozewijn D.
Navis, Gerjan
author_sort Laverman, Gozewijn D.
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description Blockade of the renin-angiotensin-aldosterone system (RAAS) offers superior renoprotection in the treatment of patients with hypertension, but the efficacy of RAAS inhibition strongly depends on sodium status, presumably in relation to extracellular volume status. Because assessing volume status by physical examination is challenging, 24-hour urine collection and NT-proBNP levels are useful tools for guiding volume management and achieving sodium status targets.
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spelling pubmed-32126962011-11-28 Improvement of Sodium Status to Optimize the Efficacy of Renin-Angiotensin System Blockade Laverman, Gozewijn D. Navis, Gerjan Curr Hypertens Rep Invited Commentary Blockade of the renin-angiotensin-aldosterone system (RAAS) offers superior renoprotection in the treatment of patients with hypertension, but the efficacy of RAAS inhibition strongly depends on sodium status, presumably in relation to extracellular volume status. Because assessing volume status by physical examination is challenging, 24-hour urine collection and NT-proBNP levels are useful tools for guiding volume management and achieving sodium status targets. Current Science Inc. 2011-10-04 2011 /pmc/articles/PMC3212696/ /pubmed/21964882 http://dx.doi.org/10.1007/s11906-011-0234-7 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Invited Commentary
Laverman, Gozewijn D.
Navis, Gerjan
Improvement of Sodium Status to Optimize the Efficacy of Renin-Angiotensin System Blockade
title Improvement of Sodium Status to Optimize the Efficacy of Renin-Angiotensin System Blockade
title_full Improvement of Sodium Status to Optimize the Efficacy of Renin-Angiotensin System Blockade
title_fullStr Improvement of Sodium Status to Optimize the Efficacy of Renin-Angiotensin System Blockade
title_full_unstemmed Improvement of Sodium Status to Optimize the Efficacy of Renin-Angiotensin System Blockade
title_short Improvement of Sodium Status to Optimize the Efficacy of Renin-Angiotensin System Blockade
title_sort improvement of sodium status to optimize the efficacy of renin-angiotensin system blockade
topic Invited Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212696/
https://www.ncbi.nlm.nih.gov/pubmed/21964882
http://dx.doi.org/10.1007/s11906-011-0234-7
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