Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

Radiotherapy is one of the most successful cancer therapies. Here the effect of irradiation on antigen presentation by MHC class I molecules was studied. Cell surface expression of MHC class I molecules was increased for many days in a radiation dose-dependent manner as a consequence of three respon...

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Detalles Bibliográficos
Autores principales: Reits, Eric A., Hodge, James W., Herberts, Carla A., Groothuis, Tom A., Chakraborty, Mala, K.Wansley, Elizabeth, Camphausen, Kevin, Luiten, Rosalie M., de Ru, Arnold H., Neijssen, Joost, Griekspoor, Alexander, Mesman, Elly, Verreck, Frank A., Spits, Hergen, Schlom, Jeffrey, van Veelen, Peter, Neefjes, Jacques J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212727/
https://www.ncbi.nlm.nih.gov/pubmed/16636135
http://dx.doi.org/10.1084/jem.20052494

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