Cargando…

The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran

BACKGROUND: Hepatitis B virus (HBV) infection is a significant health problem throughout the world. OBJECTIVES: We aimed to evaluate the prevalence of hepatitis B antigen (HBsAg) seropositivity in the general population of Mashhad, northeast of Iran. PATIENTS AND METHODS: One thousand six hundred fi...

Descripción completa

Detalles Bibliográficos
Autores principales: Fathimoghaddam, Farhad, Hedayati-Moghaddam, Mohammad Reza, Bidkhori, Hamid Reza, Ahmadi, Sanaz, Sima, Hamid Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212777/
https://www.ncbi.nlm.nih.gov/pubmed/22087159
_version_ 1782216022534651904
author Fathimoghaddam, Farhad
Hedayati-Moghaddam, Mohammad Reza
Bidkhori, Hamid Reza
Ahmadi, Sanaz
Sima, Hamid Reza
author_facet Fathimoghaddam, Farhad
Hedayati-Moghaddam, Mohammad Reza
Bidkhori, Hamid Reza
Ahmadi, Sanaz
Sima, Hamid Reza
author_sort Fathimoghaddam, Farhad
collection PubMed
description BACKGROUND: Hepatitis B virus (HBV) infection is a significant health problem throughout the world. OBJECTIVES: We aimed to evaluate the prevalence of hepatitis B antigen (HBsAg) seropositivity in the general population of Mashhad, northeast of Iran. PATIENTS AND METHODS: One thousand six hundred fifty-two healthy individuals aged 1 to 90 (Mean; 29.1 ± 18.5) from all 12 municipalities of Mashad were selected randomly by multistage cluster sampling. Informed consent was obtained, and demographics and medical histories were collected. Twice-reactive samples were considered HBsAg-positive by ELISA. Chi-square test and logistic regression were applied to analyze the factors related to HBsAg positivity using SPSS 16.0. RESULTS: The overall prevalence of HBsAg positivity was 1.39% (95% CI, 0.91% to 2.12%); 2.0% and 0.89% among men and women, respectively (p = 0.054). Infection was more prevalent in older (p = 0.019) and married persons (p = 0.001), Afghanis (p = 0.046), and those with a history of traditional cupping (p = 0.005). There was no association between HBV infection and gender; literacy; income; employment; family size; or history of blood transfusion, dental procedure, surgery, hospitalization, or tattooing. By logistic regression analysis, age was the only variable that had a significant association with infection (p = 0.026). CONCLUSION: It seems that the prevalence of HBV infection in Mashhad is slightly lower than that of the nation.
format Online
Article
Text
id pubmed-3212777
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Kowsar
record_format MEDLINE/PubMed
spelling pubmed-32127772011-11-15 The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran Fathimoghaddam, Farhad Hedayati-Moghaddam, Mohammad Reza Bidkhori, Hamid Reza Ahmadi, Sanaz Sima, Hamid Reza Hepat Mon Original Article BACKGROUND: Hepatitis B virus (HBV) infection is a significant health problem throughout the world. OBJECTIVES: We aimed to evaluate the prevalence of hepatitis B antigen (HBsAg) seropositivity in the general population of Mashhad, northeast of Iran. PATIENTS AND METHODS: One thousand six hundred fifty-two healthy individuals aged 1 to 90 (Mean; 29.1 ± 18.5) from all 12 municipalities of Mashad were selected randomly by multistage cluster sampling. Informed consent was obtained, and demographics and medical histories were collected. Twice-reactive samples were considered HBsAg-positive by ELISA. Chi-square test and logistic regression were applied to analyze the factors related to HBsAg positivity using SPSS 16.0. RESULTS: The overall prevalence of HBsAg positivity was 1.39% (95% CI, 0.91% to 2.12%); 2.0% and 0.89% among men and women, respectively (p = 0.054). Infection was more prevalent in older (p = 0.019) and married persons (p = 0.001), Afghanis (p = 0.046), and those with a history of traditional cupping (p = 0.005). There was no association between HBV infection and gender; literacy; income; employment; family size; or history of blood transfusion, dental procedure, surgery, hospitalization, or tattooing. By logistic regression analysis, age was the only variable that had a significant association with infection (p = 0.026). CONCLUSION: It seems that the prevalence of HBV infection in Mashhad is slightly lower than that of the nation. Kowsar 2011-05-01 2011-05-01 /pmc/articles/PMC3212777/ /pubmed/22087159 Text en Copyright © 2011, Kowsar M.P. Co. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Fathimoghaddam, Farhad
Hedayati-Moghaddam, Mohammad Reza
Bidkhori, Hamid Reza
Ahmadi, Sanaz
Sima, Hamid Reza
The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran
title The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran
title_full The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran
title_fullStr The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran
title_full_unstemmed The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran
title_short The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran
title_sort prevalence of hepatitis b antigen-positivity in the general population of mashhad, iran
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212777/
https://www.ncbi.nlm.nih.gov/pubmed/22087159
work_keys_str_mv AT fathimoghaddamfarhad theprevalenceofhepatitisbantigenpositivityinthegeneralpopulationofmashhadiran
AT hedayatimoghaddammohammadreza theprevalenceofhepatitisbantigenpositivityinthegeneralpopulationofmashhadiran
AT bidkhorihamidreza theprevalenceofhepatitisbantigenpositivityinthegeneralpopulationofmashhadiran
AT ahmadisanaz theprevalenceofhepatitisbantigenpositivityinthegeneralpopulationofmashhadiran
AT simahamidreza theprevalenceofhepatitisbantigenpositivityinthegeneralpopulationofmashhadiran
AT fathimoghaddamfarhad prevalenceofhepatitisbantigenpositivityinthegeneralpopulationofmashhadiran
AT hedayatimoghaddammohammadreza prevalenceofhepatitisbantigenpositivityinthegeneralpopulationofmashhadiran
AT bidkhorihamidreza prevalenceofhepatitisbantigenpositivityinthegeneralpopulationofmashhadiran
AT ahmadisanaz prevalenceofhepatitisbantigenpositivityinthegeneralpopulationofmashhadiran
AT simahamidreza prevalenceofhepatitisbantigenpositivityinthegeneralpopulationofmashhadiran