Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274

BACKGROUND: c-Met is a receptor tyrosine kinase (RTK) that is over-expressed in a variety of cancers and involved in cell growth, invasion, metastasis and angiogenesis. In this study, we investigated the role of c-Met in rhabdomyosarcoma (RMS) using its small molecule inhibitor SU11274, which has be...

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Detalles Bibliográficos
Autores principales: Hou, Jinxuan, Dong, Jixin, Sun, Lijun, Geng, Liying, Wang, Jing, Zheng, Jialin, Li, Yan, Bridge, Julia, Hinrichs, Steven H, Ding, Shi-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212957/
https://www.ncbi.nlm.nih.gov/pubmed/21575221
http://dx.doi.org/10.1186/1479-5876-9-64

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