Ultrasound microbubble-mediated delivery of the siRNAs targeting MDR1 reduces drug resistance of yolk sac carcinoma L2 cells

BACKGROUND: MDR1 gene encoding P-glycoprotein is an ATP-dependent drug efflux transporter and related to drug resistance of yolk sac carcinoma. Ultrasound microbubble-mediated delivery has been used as a novel and effective gene delivery method. We hypothesize that small interfering RNA (siRNA) targ...

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Detalles Bibliográficos
Autores principales: He, Yun, Bi, Yang, Hua, Yi, Liu, Dongyao, Wen, Sheng, Wang, Qiang, Li, Mingyong, Zhu, Jing, Lin, Tao, He, Dawei, Li, Xuliang, Wang, Zhigang, Wei, Guanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213040/
https://www.ncbi.nlm.nih.gov/pubmed/22035293
http://dx.doi.org/10.1186/1756-9966-30-104

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