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The Role of the P2X(7) Receptor in Infectious Diseases
ATP is an extracellular signal for the immune system, particularly during an inflammatory response. It is sensed by the P2X(7) receptor, the expression of which is upregulated by pro-inflammatory cytokines. Activation of the P2X(7) receptor opens a cation-specific channel that alters the ionic envir...
Autores principales: | Miller, Catherine M., Boulter, Nicola R., Fuller, Stephen J., Zakrzewski, Alana M., Lees, Michael P., Saunders, Bernadette M., Wiley, James S., Smith, Nicholas C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213081/ https://www.ncbi.nlm.nih.gov/pubmed/22102807 http://dx.doi.org/10.1371/journal.ppat.1002212 |
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