Novel Anti-bacterial Activities of β-defensin 1 in Human Platelets: Suppression of Pathogen Growth and Signaling of Neutrophil Extracellular Trap Formation

Human β-defensins (hBD) are antimicrobial peptides that curb microbial activity. Although hBD's are primarily expressed by epithelial cells, we show that human platelets express hBD-1 that has both predicted and novel antibacterial activities. We observed that activated platelets surround Staph...

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Detalles Bibliográficos
Autores principales: Kraemer, Bjoern F., Campbell, Robert A., Schwertz, Hansjörg, Cody, Mark J., Franks, Zechariah, Tolley, Neal D., Kahr, Walter H. A., Lindemann, Stephan, Seizer, Peter, Yost, Christian C., Zimmerman, Guy A., Weyrich, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213094/
https://www.ncbi.nlm.nih.gov/pubmed/22102811
http://dx.doi.org/10.1371/journal.ppat.1002355

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