Evolution of Multidrug Resistance during Staphylococcus aureus Infection Involves Mutation of the Essential Two Component Regulator WalKR

Antimicrobial resistance in Staphylococcus aureus is a major public health threat, compounded by emergence of strains with resistance to vancomycin and daptomycin, both last line antimicrobials. Here we have performed high throughput DNA sequencing and comparative genomics for five clinical pairs of...

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Detalles Bibliográficos
Autores principales: Howden, Benjamin P., McEvoy, Christopher R. E., Allen, David L., Chua, Kyra, Gao, Wei, Harrison, Paul F., Bell, Jan, Coombs, Geoffrey, Bennett-Wood, Vicki, Porter, Jessica L., Robins-Browne, Roy, Davies, John K., Seemann, Torsten, Stinear, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213104/
https://www.ncbi.nlm.nih.gov/pubmed/22102812
http://dx.doi.org/10.1371/journal.ppat.1002359

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