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Early Secreted Antigen ESAT-6 of Mycobacterium tuberculosis Promotes Protective T Helper 17 Cell Responses in a Toll-Like Receptor-2-dependent Manner

Despite its relatively poor efficacy, Bacillus Calmette-Guérin (BCG) has been used as a tuberculosis (TB) vaccine since its development in 1921. BCG induces robust T helper 1 (Th1) immune responses but, for many individuals, this is not sufficient for host resistance against Mycobacterium tuberculos...

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Detalles Bibliográficos
Autores principales:	Chatterjee, Samit, Dwivedi, Ved Prakash, Singh, Yogesh, Siddiqui, Imran, Sharma, Pawan, Van Kaer, Luc, Chattopadhyay, Debprasad, Das, Gobardhan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213116/ https://www.ncbi.nlm.nih.gov/pubmed/22102818 http://dx.doi.org/10.1371/journal.ppat.1002378

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