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Rapid Colorimetric Testing for Pyrazinamide Susceptibility of M. tuberculosis by a PCR-Based In-Vitro Synthesized Pyrazinamidase Method
Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug. But PZA susceptibility test is challenging because PZA activity is optimal only in an acid environment that inhibits the growth of M. tuberculosis. For current phenotypic methods, inconsistent results between different labs have b...
Autores principales: | Zhou, Man, Geng, Xuelei, Chen, Jun, Wang, Xude, Wang, Dianbing, Deng, Jiaoyu, Zhang, Zhiping, Wang, Weihua, Zhang, Xian-En, Wei, Hongping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213173/ https://www.ncbi.nlm.nih.gov/pubmed/22102918 http://dx.doi.org/10.1371/journal.pone.0027654 |
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