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Hypoxia inducible factor-1 alpha expression is increased in infected positive HPV16 DNA oral squamous cell carcinoma and positively associated with HPV16 E7 oncoprotein

BACKGROUND: There is increasing evidence for the role of High Risk (HR) Human PapillomaVirus (HPV) in the pathogenesis of Oral Squamous Cell Carcinoma (OSCC). The E6 and E7 oncogenes from HR HPVs are responsible for the deregulation of p53 and pRB proteins involved in cell cycle and apoptotic pathwa...

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Detalles Bibliográficos
Autores principales:	Rodolico, Vito, Arancio, Walter, Amato, Marco C, Aragona, Francesco, Cappello, Francesco, Di Fede, Olga, Pannone, Giuseppe, Campisi, Giuseppina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213191/ https://www.ncbi.nlm.nih.gov/pubmed/22032288 http://dx.doi.org/10.1186/1750-9378-6-18

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