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Overexpression of hepatoma-derived growth factor in melanocytes does not lead to oncogenic transformation

BACKGROUND: HDGF is a growth factor which is overexpressed in a wide range of tumors. Importantly, expression levels were identified as a prognostic marker in some types of cancer such as melanoma. METHODS: To investigate the presumed oncogenic/transforming capacity of HDGF, we generated transgenic...

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Detalles Bibliográficos
Autores principales: Sedlmaier, Angela, Wernert, Nicolas, Gallitzendörfer, Rainer, Abouzied, Mekky M, Gieselmann, Volkmar, Franken, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213223/
https://www.ncbi.nlm.nih.gov/pubmed/22014102
http://dx.doi.org/10.1186/1471-2407-11-457