Cargando…

Overexpression of hepatoma-derived growth factor in melanocytes does not lead to oncogenic transformation

BACKGROUND: HDGF is a growth factor which is overexpressed in a wide range of tumors. Importantly, expression levels were identified as a prognostic marker in some types of cancer such as melanoma. METHODS: To investigate the presumed oncogenic/transforming capacity of HDGF, we generated transgenic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sedlmaier, Angela, Wernert, Nicolas, Gallitzendörfer, Rainer, Abouzied, Mekky M, Gieselmann, Volkmar, Franken, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213223/ https://www.ncbi.nlm.nih.gov/pubmed/22014102 http://dx.doi.org/10.1186/1471-2407-11-457

Ejemplares similares

Hepatoma-derived growth factor and nucleolin exist in the same ribonucleoprotein complex
por: Bremer, Stephanie, et al.
Publicado: (2013)

Expression of Hepatoma-derived growth factor family members in the adult central nervous system
por: El-Tahir, Heba M, et al.
Publicado: (2006)

Dysregulation of MITF Leads to Transformation in MC1R-Defective Melanocytes
por: Lavelle, Timothy J., et al.
Publicado: (2020)

Transformation of murine melanocytes by basic fibroblast growth factor cDNA and oncogenes and selective suppression of the transformed phenotype in a reconstituted cutaneous environment
Publicado: (1989)

The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence
por: Haferkamp, Sebastian, et al.
Publicado: (2009)

CEACAM1: Expression and Role in Melanocyte Transformation
por: Turcu, Gabriela, et al.
Publicado: (2016)

Scale-Aware Transformers for Diagnosing Melanocytic Lesions
por: WU, WENJUN, et al.
Publicado: (2021)

Hepatoprotective activity of ethanolic extract of Salix subserrata against CCl(4)-induced chronic hepatotoxicity in rats
por: Wahid, Ahmed, et al.
Publicado: (2016)

Cell surface antigens of human melanocytes and melanoma. Expression of adenosine deaminase binding protein is extinguished with melanocyte transformation
Publicado: (1988)

A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation
por: Grassilli, E, et al.
Publicado: (2016)

Oncogenic Transformation of Dendritic Cells and Their Precursors Leads to Rapid Cancer Development in Mice
por: Böttcher, Jan P., et al.
Publicado: (2015)

Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction
por: Ito, Reina E., et al.
Publicado: (2021)

Induction of Apurinic Endonuclease 1 Overexpression by Endoplasmic Reticulum Stress in Hepatoma Cells
por: Cheng, Tsung-Lin, et al.
Publicado: (2014)

Overexpression of c-Jun contributes to sorafenib resistance in human hepatoma cell lines
por: Haga, Yuki, et al.
Publicado: (2017)

Investigation of Radiotracer Metabolic Stability In Vitro with CYP-Overexpressing Hepatoma Cell Lines
por: Lemm, Sandy, et al.
Publicado: (2022)

Oncogenic BRAF mutations and p16 expression in melanocytic nevi and melanoma in the Polish population
por: Mackiewicz-Wysocka, Małgorzata, et al.
Publicado: (2017)

Does Melanoma Begin in a Melanocyte Stem Cell?
por: Hoerter, James D., et al.
Publicado: (2012)

Hepatoma-derived growth factor/nucleolin axis as a novel oncogenic pathway in liver carcinogenesis
por: Chen, San-Cher, et al.
Publicado: (2015)

The human Rgr oncogene is overexpressed in T cell malignancies and induces transformation by acting as a GEF for Ras and Ral
por: Osei-Sarfo, Kwame, et al.
Publicado: (2011)

MITF deficiency and oncogenic GNAQ each promote proliferation programs in zebrafish melanocyte lineage cells
por: Phelps, Grace B., et al.
Publicado: (2022)

Mélanocytes épidermiques et mélanocytes folliculaires
por: Ortonne, JP, et al.
Publicado: (1981)

Asbestos, radiation and oncogenic transformation.
por: Hei, T. K., et al.
Publicado: (1984)

Accumulation of lysosulfatide in the brain of arylsulfatase A-deficient mice
por: Blomqvist, Maria, et al.
Publicado: (2011)

Expression of SEC62 Oncogene in Benign, Malignant and Borderline Melanocytic Tumors—Unmasking the Wolf in Sheep’s Clothing?
por: Müller, Cornelia S. L., et al.
Publicado: (2021)

Evidence That SOX2 Overexpression Is Oncogenic in the Lung
por: Lu, Yun, et al.
Publicado: (2010)

Hepatoma SK Hep-1 Cells Exhibit Characteristics of Oncogenic Mesenchymal Stem Cells with Highly Metastatic Capacity
por: Eun, Jong Ryeol, et al.
Publicado: (2014)

Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes
por: Ruiz-Vega, Rolando, et al.
Publicado: (2020)

Potentiation of Invasive Capacity of Rat Ascites Hepatoma Cells by Transforming Growth Factor‐β
por: Mukai, Mutsuko, et al.
Publicado: (1989)

Histochemical evidence that peroxidase does not affect melanin formation in feather melanocytes.
por: Brumbaugh, J., et al.
Publicado: (1973)

Immortality, but not oncogenic transformation, of primary human cells leads to epigenetic reprogramming of DNA methylation and gene expression
por: Gordon, Katrina, et al.
Publicado: (2014)

Potentiation of Epidermal Growth Factor-Mediated Oncogenic Transformation by Sialidase NEU3 Leading to Src Activation
por: Yamamoto, Koji, et al.
Publicado: (2015)

Non-Melanocytic Tumors of the Skin and Melanocytic Tumors of the Skin
por: Kirkham, N.
Publicado: (1992)

Targeting anti-apoptotic pathways eliminates senescent melanocytes and leads to nevi regression
por: Kohli, Jaskaren, et al.
Publicado: (2022)

Antioxidant, anti-inflammatory and anti-fibrotic effects of Boswellia serrate gum resin in CCl(4)-induced hepatotoxicity
por: Eltahir, Heba M., et al.
Publicado: (2020)

Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function
por: van Tuyn, John, et al.
Publicado: (2017)

A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease
por: Sun, Qi, et al.
Publicado: (2019)

Common Benign Melanocytic and Non-Melanocytic Skin Tumors among the Elderly: Results of the Graz Study on Health and Aging
por: Gruber, Viktoria, et al.
Publicado: (2023)

Pokemon Silencing Leads to Bim-Mediated Anoikis of Human Hepatoma Cell QGY7703
por: Liu, Kun, et al.
Publicado: (2012)

Transforming ras oncogenes and multistage carcinogenesis.
por: Balmain, A.
Publicado: (1985)

Reversing oncogenic transformation with iron chelation
por: Abdelaal, Gina, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mr7qcphdsdin5fbc0kllemc3c2