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Meiotic functions of RAD18

RAD18 is an ubiquitin ligase that is involved in replication damage bypass and DNA double-strand break (DSB) repair processes in mitotic cells. Here, we investigated the testicular phenotype of Rad18-knockdown mice to determine the function of RAD18 in meiosis, and in particular, in the repair of me...

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Detalles Bibliográficos
Autores principales: Inagaki, Akiko, Sleddens-Linkels, Esther, Wassenaar, Evelyne, Ooms, Marja, van Cappellen, Wiggert A., Hoeijmakers, Jan H. J., Seibler, Jost, Vogt, Thomas F., Shin, Myung K., Grootegoed, J. Anton, Baarends, Willy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213229/
https://www.ncbi.nlm.nih.gov/pubmed/21807948
http://dx.doi.org/10.1242/jcs.081968