(9S,13R,14S)-7,8-Didehydro-4-(4-fluoro­benz­yloxy)-3,7-dimeth­oxy-17-methyl­morphinan-6-one sesquihydrate

In the title sinomenine derivative, C(26)H(28)FNO(4)·1.5H(2)O, the dihedral angle between the two aromatic rings is 55.32 (6)°. The N-containing ring has an approximate chair conformation, while other two rings have approximate envelope and half-chair conformations. One water mol­ecule is located on...

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Autores principales: Zheng, Xing-Liang, Jiang, Ning-Fei, Luo, Dan, Gao, Hong-Sheng, Ding, Ai-Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213444/
https://www.ncbi.nlm.nih.gov/pubmed/22091023
http://dx.doi.org/10.1107/S1600536811026183
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author Zheng, Xing-Liang
Jiang, Ning-Fei
Luo, Dan
Gao, Hong-Sheng
Ding, Ai-Shun
author_facet Zheng, Xing-Liang
Jiang, Ning-Fei
Luo, Dan
Gao, Hong-Sheng
Ding, Ai-Shun
author_sort Zheng, Xing-Liang
collection PubMed
description In the title sinomenine derivative, C(26)H(28)FNO(4)·1.5H(2)O, the dihedral angle between the two aromatic rings is 55.32 (6)°. The N-containing ring has an approximate chair conformation, while other two rings have approximate envelope and half-chair conformations. One water mol­ecule is located on a twofold symmetry axis. In the crystal, the water mol­ecules form O—H⋯O and O—H⋯N hydrogen bonds, bridging symmetry-related main mol­ecules.
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spelling pubmed-32134442011-11-16 (9S,13R,14S)-7,8-Didehydro-4-(4-fluoro­benz­yloxy)-3,7-dimeth­oxy-17-methyl­morphinan-6-one sesquihydrate Zheng, Xing-Liang Jiang, Ning-Fei Luo, Dan Gao, Hong-Sheng Ding, Ai-Shun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title sinomenine derivative, C(26)H(28)FNO(4)·1.5H(2)O, the dihedral angle between the two aromatic rings is 55.32 (6)°. The N-containing ring has an approximate chair conformation, while other two rings have approximate envelope and half-chair conformations. One water mol­ecule is located on a twofold symmetry axis. In the crystal, the water mol­ecules form O—H⋯O and O—H⋯N hydrogen bonds, bridging symmetry-related main mol­ecules. International Union of Crystallography 2011-07-09 /pmc/articles/PMC3213444/ /pubmed/22091023 http://dx.doi.org/10.1107/S1600536811026183 Text en © Zheng et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Zheng, Xing-Liang
Jiang, Ning-Fei
Luo, Dan
Gao, Hong-Sheng
Ding, Ai-Shun
(9S,13R,14S)-7,8-Didehydro-4-(4-fluoro­benz­yloxy)-3,7-dimeth­oxy-17-methyl­morphinan-6-one sesquihydrate
title (9S,13R,14S)-7,8-Didehydro-4-(4-fluoro­benz­yloxy)-3,7-dimeth­oxy-17-methyl­morphinan-6-one sesquihydrate
title_full (9S,13R,14S)-7,8-Didehydro-4-(4-fluoro­benz­yloxy)-3,7-dimeth­oxy-17-methyl­morphinan-6-one sesquihydrate
title_fullStr (9S,13R,14S)-7,8-Didehydro-4-(4-fluoro­benz­yloxy)-3,7-dimeth­oxy-17-methyl­morphinan-6-one sesquihydrate
title_full_unstemmed (9S,13R,14S)-7,8-Didehydro-4-(4-fluoro­benz­yloxy)-3,7-dimeth­oxy-17-methyl­morphinan-6-one sesquihydrate
title_short (9S,13R,14S)-7,8-Didehydro-4-(4-fluoro­benz­yloxy)-3,7-dimeth­oxy-17-methyl­morphinan-6-one sesquihydrate
title_sort (9s,13r,14s)-7,8-didehydro-4-(4-fluoro­benz­yloxy)-3,7-dimeth­oxy-17-methyl­morphinan-6-one sesquihydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213444/
https://www.ncbi.nlm.nih.gov/pubmed/22091023
http://dx.doi.org/10.1107/S1600536811026183
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