N-(2-Amino-3,5-dibromo­benz­yl)-N-methyl­cyclo­hexan-1-aminium p-toluenesulfonate

The title compound, C(14)H(21)Br(2)N(2) (+)·C(7)H(7)O(3)S(−), features a salt of protonated bromhexine, a pharmaceutical used in the treatment of respiratory disorders, and the p-toluenesulfonate anion. The crystal packing is stabilized by inter­molecular N—H⋯O, N—H⋯Br and C—H⋯O hydrogen bonds....

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Detalles Bibliográficos
Autores principales: Maste, Meenaxi M., Mahapatra, Sudarshan, Ramachandran, Krishna Kumar, Venugopala, K. N., Bhat, A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213481/
https://www.ncbi.nlm.nih.gov/pubmed/22091060
http://dx.doi.org/10.1107/S1600536811027358
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author Maste, Meenaxi M.
Mahapatra, Sudarshan
Ramachandran, Krishna Kumar
Venugopala, K. N.
Bhat, A. R.
author_facet Maste, Meenaxi M.
Mahapatra, Sudarshan
Ramachandran, Krishna Kumar
Venugopala, K. N.
Bhat, A. R.
author_sort Maste, Meenaxi M.
collection PubMed
description The title compound, C(14)H(21)Br(2)N(2) (+)·C(7)H(7)O(3)S(−), features a salt of protonated bromhexine, a pharmaceutical used in the treatment of respiratory disorders, and the p-toluenesulfonate anion. The crystal packing is stabilized by inter­molecular N—H⋯O, N—H⋯Br and C—H⋯O hydrogen bonds.
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spelling pubmed-32134812011-11-16 N-(2-Amino-3,5-dibromo­benz­yl)-N-methyl­cyclo­hexan-1-aminium p-toluenesulfonate Maste, Meenaxi M. Mahapatra, Sudarshan Ramachandran, Krishna Kumar Venugopala, K. N. Bhat, A. R. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(14)H(21)Br(2)N(2) (+)·C(7)H(7)O(3)S(−), features a salt of protonated bromhexine, a pharmaceutical used in the treatment of respiratory disorders, and the p-toluenesulfonate anion. The crystal packing is stabilized by inter­molecular N—H⋯O, N—H⋯Br and C—H⋯O hydrogen bonds. International Union of Crystallography 2011-07-13 /pmc/articles/PMC3213481/ /pubmed/22091060 http://dx.doi.org/10.1107/S1600536811027358 Text en © Maste et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Maste, Meenaxi M.
Mahapatra, Sudarshan
Ramachandran, Krishna Kumar
Venugopala, K. N.
Bhat, A. R.
N-(2-Amino-3,5-dibromo­benz­yl)-N-methyl­cyclo­hexan-1-aminium p-toluenesulfonate
title N-(2-Amino-3,5-dibromo­benz­yl)-N-methyl­cyclo­hexan-1-aminium p-toluenesulfonate
title_full N-(2-Amino-3,5-dibromo­benz­yl)-N-methyl­cyclo­hexan-1-aminium p-toluenesulfonate
title_fullStr N-(2-Amino-3,5-dibromo­benz­yl)-N-methyl­cyclo­hexan-1-aminium p-toluenesulfonate
title_full_unstemmed N-(2-Amino-3,5-dibromo­benz­yl)-N-methyl­cyclo­hexan-1-aminium p-toluenesulfonate
title_short N-(2-Amino-3,5-dibromo­benz­yl)-N-methyl­cyclo­hexan-1-aminium p-toluenesulfonate
title_sort n-(2-amino-3,5-dibromo­benz­yl)-n-methyl­cyclo­hexan-1-aminium p-toluenesulfonate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213481/
https://www.ncbi.nlm.nih.gov/pubmed/22091060
http://dx.doi.org/10.1107/S1600536811027358
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