(5S)-3-Chloro-4-diallyl­amino-5-[(1R,2S,5R)-2-isopropyl-5-methyl­cyclo­hex­yloxy]furan-2(5H)-one

The title compound, C(20)H(30)ClNO(3), was obtained via a tandem asymmetric Michael addition–elimination reaction of (5S)-3,4-dichloro-5-(l-menth­yloxy)-2(5H)-furan­one and diallyl­amine in the presence of potassium fluoride. The mol­ecular structure contains an approximately planar five-membered fu...

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Detalles Bibliográficos
Autores principales: Huang, Dong-Na, Tan, Yue-He, Fu, Jian-Hua, Wang, Zhao-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213497/
https://www.ncbi.nlm.nih.gov/pubmed/22091076
http://dx.doi.org/10.1107/S1600536811027772
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author Huang, Dong-Na
Tan, Yue-He
Fu, Jian-Hua
Wang, Zhao-Yang
author_facet Huang, Dong-Na
Tan, Yue-He
Fu, Jian-Hua
Wang, Zhao-Yang
author_sort Huang, Dong-Na
collection PubMed
description The title compound, C(20)H(30)ClNO(3), was obtained via a tandem asymmetric Michael addition–elimination reaction of (5S)-3,4-dichloro-5-(l-menth­yloxy)-2(5H)-furan­one and diallyl­amine in the presence of potassium fluoride. The mol­ecular structure contains an approximately planar five-membered furan­one ring [maximum atomic deviation = 0.0221 (3) Å] and a six-membered ring adopting a chair conformation.
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spelling pubmed-32134972011-11-16 (5S)-3-Chloro-4-diallyl­amino-5-[(1R,2S,5R)-2-isopropyl-5-methyl­cyclo­hex­yloxy]furan-2(5H)-one Huang, Dong-Na Tan, Yue-He Fu, Jian-Hua Wang, Zhao-Yang Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(20)H(30)ClNO(3), was obtained via a tandem asymmetric Michael addition–elimination reaction of (5S)-3,4-dichloro-5-(l-menth­yloxy)-2(5H)-furan­one and diallyl­amine in the presence of potassium fluoride. The mol­ecular structure contains an approximately planar five-membered furan­one ring [maximum atomic deviation = 0.0221 (3) Å] and a six-membered ring adopting a chair conformation. International Union of Crystallography 2011-07-16 /pmc/articles/PMC3213497/ /pubmed/22091076 http://dx.doi.org/10.1107/S1600536811027772 Text en © Huang et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Huang, Dong-Na
Tan, Yue-He
Fu, Jian-Hua
Wang, Zhao-Yang
(5S)-3-Chloro-4-diallyl­amino-5-[(1R,2S,5R)-2-isopropyl-5-methyl­cyclo­hex­yloxy]furan-2(5H)-one
title (5S)-3-Chloro-4-diallyl­amino-5-[(1R,2S,5R)-2-isopropyl-5-methyl­cyclo­hex­yloxy]furan-2(5H)-one
title_full (5S)-3-Chloro-4-diallyl­amino-5-[(1R,2S,5R)-2-isopropyl-5-methyl­cyclo­hex­yloxy]furan-2(5H)-one
title_fullStr (5S)-3-Chloro-4-diallyl­amino-5-[(1R,2S,5R)-2-isopropyl-5-methyl­cyclo­hex­yloxy]furan-2(5H)-one
title_full_unstemmed (5S)-3-Chloro-4-diallyl­amino-5-[(1R,2S,5R)-2-isopropyl-5-methyl­cyclo­hex­yloxy]furan-2(5H)-one
title_short (5S)-3-Chloro-4-diallyl­amino-5-[(1R,2S,5R)-2-isopropyl-5-methyl­cyclo­hex­yloxy]furan-2(5H)-one
title_sort (5s)-3-chloro-4-diallyl­amino-5-[(1r,2s,5r)-2-isopropyl-5-methyl­cyclo­hex­yloxy]furan-2(5h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213497/
https://www.ncbi.nlm.nih.gov/pubmed/22091076
http://dx.doi.org/10.1107/S1600536811027772
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