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(Z)-3α-(1,3-Dioxoisoindolin-2-yl)-17(20)-pregnene
The title compound, C(29)H(37)NO(2), crystallized with two independent molecules in an asymmetric unit in which the conformation of the cyclohexyl ring of the pregnene moiety bonded to the 3α-(1,3-dioxoisoindolin-2-yl)- ring system differs: in one molecule it is in a chair conformation, while in...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213511/ https://www.ncbi.nlm.nih.gov/pubmed/22091090 http://dx.doi.org/10.1107/S1600536811027632 |
Sumario: | The title compound, C(29)H(37)NO(2), crystallized with two independent molecules in an asymmetric unit in which the conformation of the cyclohexyl ring of the pregnene moiety bonded to the 3α-(1,3-dioxoisoindolin-2-yl)- ring system differs: in one molecule it is in a chair conformation, while in the other it exhibits a half-chair conformation. The other six-membered rings in the pregnene moiety are in chair conformations and the five-membered rings are in envelope forms in both molecules. In both molecules, the 3α-(1,3-dioxoisoindolin-2-yl)- ring systems are individually approximately planar, with r.m.s. devtaions 0.0148 and 0.0264 Å. The structure is consolidated by intermolecular C—H⋯O hydrogen-bonding interactions involving the carbonyl O atoms and methyl, methylene and methylidyne groups, resulting in a two-dimensional structure. |
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