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(R)-(+)-2-{[(3-Methyl-4-nitro­pyridin-2-yl)meth­yl]sulfin­yl}-1H-benzimidazole

The title compound, C(14)H(12)N(4)O(3)S, is an inter­mediate of Dexlansoprazole, a proton pump inhibitor (PPI) mainly developed for anti-ulcer activity. The absolute configuration of the title compound was determined as R. The crystal structure reveals that the mol­ecules form chains along the b axi...

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Detalles Bibliográficos
Autores principales: Naga Raju, Manne, Uday Kumar, Neelam, Kolla, Naveenkumar, Bandichhor, Rakeshwar, Vishweshwar, Peddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213621/
https://www.ncbi.nlm.nih.gov/pubmed/22091198
http://dx.doi.org/10.1107/S1600536811029990