Phosphatidylinositol (4,5) Bisphosphate Controls T Cell Activation by Regulating T Cell Rigidity and Organization

Here we investigate the role of Phosphatidylinositol (4,5) bisphosphate (PIP(2)) in the physiological activation of primary murine T cells by antigen presenting cells (APC) by addressing two principal challenges in PIP(2) biology. First, PIP(2) is a regulator of cytoskeletal dynamics and a substrate...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Yi, Dandekar, Radhika D., Mao, Yuntao S., Yin, Helen L., Wülfing, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214035/
https://www.ncbi.nlm.nih.gov/pubmed/22096541
http://dx.doi.org/10.1371/journal.pone.0027227

Ejemplares similares

Ejemplares similares