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A Role for the Ubiquitin Ligase Nedd4 in Membrane Sorting of LAPTM4 Proteins
BACKGROUND: The Lysosome associated protein transmembrane (LAPTM) family is comprised of three members: LAPTM5, LAPTM4a and LAPTM4b, with the latter previously shown to be overexpressed in numerous cancers. While we had demonstrated earlier the requirement of the E3 ubiquitin ligase Nedd4 for LAPTM5...
Autores principales: | Milkereit, Ruth, Rotin, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214061/ https://www.ncbi.nlm.nih.gov/pubmed/22096579 http://dx.doi.org/10.1371/journal.pone.0027478 |
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