Up-Regulation of A1M/α(1)-Microglobulin in Skin by Heme and Reactive Oxygen Species Gives Protection from Oxidative Damage

During bleeding the skin is subjected to oxidative insults from free heme and radicals, generated from extracellular hemoglobin. The lipocalin α(1)-microglobulin (A1M) was recently shown to have reductase properties, reducing heme-proteins and other substrates, and to scavenge heme and radicals. We...

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Detalles Bibliográficos
Autores principales: Olsson, Magnus G., Allhorn, Maria, Larsson, Jörgen, Cederlund, Martin, Lundqvist, Katarina, Schmidtchen, Artur, Sørensen, Ole E., Mörgelin, Matthias, Åkerström, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214066/
https://www.ncbi.nlm.nih.gov/pubmed/22096585
http://dx.doi.org/10.1371/journal.pone.0027505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214066/
https://www.ncbi.nlm.nih.gov/pubmed/22096585
http://dx.doi.org/10.1371/journal.pone.0027505

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