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Antibiotics Shaping Bacterial Genome: Deletion of an IS91 Flanked Virulence Determinant upon Exposure to Subinhibitory Antibiotic Concentrations

The nucleoid-associated proteins Hha and YdgT repress the expression of the toxin α-hemolysin. An Escherichia coli mutant lacking these proteins overexpresses the toxin α-hemolysin encoded in the multicopy recombinant plasmid pANN202-312R. Unexpectedly, we could observe that this mutant generated cl...

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Detalles Bibliográficos
Autores principales:	Pedró, Laura, Baños, Rosa C., Aznar, Sonia, Madrid, Cristina, Balsalobre, Carlos, Juárez, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214074/ https://www.ncbi.nlm.nih.gov/pubmed/22096603 http://dx.doi.org/10.1371/journal.pone.0027606

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