Cargando…

The PHD Finger of Human UHRF1 Reveals a New Subgroup of Unmethylated Histone H3 Tail Readers

The human UHRF1 protein (ubiquitin-like containing PHD and RING finger domains 1) has emerged as a potential cancer target due to its implication in cell cycle regulation, maintenance of DNA methylation after replication and heterochromatin formation. UHRF1 functions as an adaptor protein that binds...

Descripción completa

Detalles Bibliográficos
Autores principales: Lallous, Nada, Legrand, Pierre, McEwen, Alastair G., Ramón-Maiques, Santiago, Samama, Jean-Pierre, Birck, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214078/
https://www.ncbi.nlm.nih.gov/pubmed/22096602
http://dx.doi.org/10.1371/journal.pone.0027599

Ejemplares similares