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Comparison of nanoparticle-mediated transfection methods for DNA expression plasmids: efficiency and cytotoxicity

BACKGROUND: Reproducibly high transfection rates with low methodology-induced cytotoxic side effects are essential to attain the required effect on targeted cells when exogenous DNA is transfected. Different approaches and modifications such as the use of nanoparticles (NPs) are being evaluated to i...

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Detalles Bibliográficos
Autores principales: Durán, María Carolina, Willenbrock, Saskia, Barchanski, Annette, Müller, Jessika-M V, Maiolini, Arianna, Soller, Jan T, Barcikowski, Stephan, Nolte, Ingo, Feige, Karsten, Murua Escobar, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214154/
https://www.ncbi.nlm.nih.gov/pubmed/22014272
http://dx.doi.org/10.1186/1477-3155-9-47