Cargando…

TP53 mutation p.R337H in gastric cancer tissues of a 12-year-old male child - evidence for chimerism involving a common mutant founder haplotype: case report

BACKGROUND: Gastric adenocarcinoma is rare in children and adolescents, with about 17 cases under age 21 in the world's literature. We report a case of invasive well-differentiated metastatic gastric cancer in a Brazilian 12-year-old boy without documented familial history of cancer. CASE PRESE...

Descripción completa

Detalles Bibliográficos
Autores principales:	da Silva, Edaise M, W Achatz, Maria Isabel, Martel-Planche, Ghyslaine, Montagnini, André L, Olivier, Magali, Prolla, Patricia A, Hainaut, Pierre, Soares, Fernando A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214196/ https://www.ncbi.nlm.nih.gov/pubmed/22004116 http://dx.doi.org/10.1186/1471-2407-11-449

Ejemplares similares

Prevalence of the TP53 p.R337H Mutation in Breast Cancer Patients in Brazil
por: Giacomazzi, Juliana, et al.
Publicado: (2014)

Ancestry of the Brazilian TP53 c.1010G>A (p.Arg337His, R337H) Founder Mutation: Clues from Haplotyping of Short Tandem Repeats on Chromosome 17p
por: Paskulin, Diego Davila, et al.
Publicado: (2015)

Comparison of multiple genotyping methods for the identification of the cancer predisposing founder mutation p.R337H inTP53
por: Fitarelli-Kiehl, Mariana, et al.
Publicado: (2016)

Increased Oxidative Damage in Carriers of the Germline TP53 p.R337H Mutation
por: Macedo, Gabriel S., et al.
Publicado: (2012)

Multiple TP53 p.R337H haplotypes and implications for tumor susceptibility
por: Pinto, Emilia M., et al.
Publicado: (2023)

Prevalence of the Brazilian TP53 Founder c.1010G>A (p.Arg337His) in Lung Adenocarcinoma: Is Genotyping Warranted in All Brazilian Patients?
por: Vieira, Igor Araujo, et al.
Publicado: (2021)

TP53 p.R337H is a conditional cancer-predisposing mutation: further evidence from a homozygous patient
por: Giacomazzi, Juliana, et al.
Publicado: (2013)

Low Prevalence of TP53 Mutations and MDM2 Amplifications in Pediatric Rhabdomyosarcoma
por: Ognjanovic, Simona, et al.
Publicado: (2012)

Occurrence of Neuroblastoma among TP53 p.R337H Carriers
por: Seidinger, Ana Luiza, et al.
Publicado: (2015)

Early-onset breast cancer patients in the South and Southeast of Brazil should be tested for the TP53 p.R337H mutation
por: Andrade, Kelvin C., et al.
Publicado: (2016)

Breast Cancer Phenotype Associated With Li-Fraumeni Syndrome: A Brazilian Cohort Enriched by TP53 p.R337H Carriers
por: Sandoval, Renata Lazari, et al.
Publicado: (2022)

TP53 p.R337H prevalence in a series of Brazilian hereditary breast cancer families
por: Cury, Nathalia M, et al.
Publicado: (2014)

Identification of the TP53 p.R337H Variant in Tumor Genomic Profiling Should Prompt Consideration of Germline Testing for Li-Fraumeni Syndrome
por: Sandoval, Renata Lazari, et al.
Publicado: (2021)

The Brazilian TP53 mutation (R337H) and sarcomas
por: Volc, Sahlua Miguel, et al.
Publicado: (2020)

What 20 years of research has taught us about the TP53 p.R337H mutation
por: Pinto, Emilia Modolo, et al.
Publicado: (2020)

Environmental Contaminants Modulate Breast Cancer Development and Outcome in TP53 p.R337H Carriers and Noncarriers
por: Gerber, Viviane K. Q., et al.
Publicado: (2022)

The TP53 fertility network
por: Paskulin, Diego d’Avila, et al.
Publicado: (2012)

The R337H mutation in TP53 and breast cancer in Brazil
por: Gomes, Magda CB, et al.
Publicado: (2012)

Modeling the prevalent germline TP53 R337H mutation in mouse
por: Park, Ji-Hoon, et al.
Publicado: (2019)

Association of the germline TP53 R337H mutation with breast cancer in southern Brazil
por: Assumpção, Juliana G, et al.
Publicado: (2011)

Association of the germline TP53 R337H mutation with breast cancer in southern Brazil
por: Assumpção, Juliana G, et al.
Publicado: (2008)

TP53 p.Arg337His geographic distribution correlates with adrenocortical tumor occurrence
por: Seidinger, Ana L., et al.
Publicado: (2020)

TP53 mutations, amplification of P63 and expression of cell cycle proteins in squamous cell carcinoma of the oesophagus from a low incidence area in Western Europe
por: Tanière, P, et al.
Publicado: (2001)

TP53 mutations, human papilloma virus DNA and inflammation markers in esophageal squamous cell carcinoma from the Rift Valley, a high-incidence area in Kenya
por: Patel, Kirtika, et al.
Publicado: (2011)

TP53 p.Arg337His germline mutation prevalence in Southern Brazil: Further evidence for mutation testing in young breast cancer patients
por: Hahn, Eriza Cristina, et al.
Publicado: (2018)

Studies of TP53 haplotypes in relation to LOH and TP53 mutations in breast cancer patients
por: Langerød, A, et al.
Publicado: (2000)

Frequency of the TP53 R337H variant in sporadic breast cancer and its impact on genomic instability
por: Mathias, Carolina, et al.
Publicado: (2020)

The Clinical and Molecular Profile of Lung Cancer Patients Harboring the TP53 R337H Germline Variant in a Brazilian Cancer Center: The Possible Mechanism of Carcinogenesis
por: Lopes, Carlos D. H., et al.
Publicado: (2023)

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis
por: Leroy, Bernard, et al.
Publicado: (2013)

The profile and contribution of rare germline copy number variants to cancer risk in Li-Fraumeni patients negative for TP53 mutations
por: Silva, Amanda G, et al.
Publicado: (2014)

Analysis of the Li-Fraumeni Spectrum Based on an International Germline TP53 Variant Data Set: An International Agency for Research on Cancer TP53 Database Analysis
por: Kratz, Christian P., et al.
Publicado: (2021)

Increased Incidence of Choroid Plexus Carcinoma Due to the Germline TP53 R337H Mutation in Southern Brazil
por: Custodio, Gislaine, et al.
Publicado: (2011)

TP53 PIN3 and PEX4 polymorphisms and infertility associated with endometriosis or with post-in vitro fertilization implantation failure
por: Paskulin, D D, et al.
Publicado: (2012)

Number of rare germline CNVs and TP53 mutation types
por: Silva, Amanda G, et al.
Publicado: (2012)

Hepatitis B and Hepatitis C Infection Biomarkers and TP53 Mutations in Hepatocellular Carcinomas from Colombia
por: Navas, Maria-Cristina, et al.
Publicado: (2011)

Regulators of Oncogenic Mutant TP53 Gain of Function
por: Yamamoto, Satomi, et al.
Publicado: (2018)

Lessons from TP53 mutations in breast cancers: from carcinogen fingerprints to clinical correlates
por: Hainaut, P, et al.
Publicado: (2000)

Haplotype and linkage disequilibrium of TP53-WRAP53 locus in Iranian-Azeri women with breast cancer
por: Pouladi, Nasser, et al.
Publicado: (2019)

TP53 Mutations and HBX Status Analysis in Hepatocellular Carcinomas from Iran: Evidence for Lack of Association between HBV Genotype D and TP53 R249S Mutations
por: Abedi-Ardekani, Behnoush, et al.
Publicado: (2011)

Newborn Screening for the Detection of the TP53 R337H Variant and Surveillance for Early Diagnosis of Pediatric Adrenocortical Tumors: Lessons Learned and Way Forward
por: Tosin, Karina C. F., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_nnc3fepkuejq6ho454b2tnuf93