Cargando…

Deletion of ABL/BCR on der(9) associated with severe basophilia

Chronic basophilic leukemia is a rare form in chronic myeloid leukemia patients. Only limited number of reports are available. Herein, we describe a patient who presented with fatigue, weight loss, leucocytosis, prominent basophilia, and mild eosinophilia. On biopsy, bone marrow was hypercellular wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vaidya, Shantashri, Madkaikar, Manisha, Ghosh, Kanjaksha, Vundinti, Babu Rao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications 2011
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214311/ https://www.ncbi.nlm.nih.gov/pubmed/22090723 http://dx.doi.org/10.4103/0971-6866.86198

Ejemplares similares

Evolution of BCR/ABL Gene Mutation in CML Is Time Dependent and Dependent on the Pressure Exerted by Tyrosine Kinase Inhibitor
por: Vaidya, Shantashri, et al.
Publicado: (2015)

Octaploidy in idiopathic thrombocytopenia purpura: Is it incidental or causal?
por: Vaidya, Shantashri, et al.
Publicado: (2012)

A first case of primary amenorrhea with i(X)(qter---q10::---qter), rob(13;14)(q10;q10), inv(9)(p13q33) karyotype
por: Korgaonkar, Seema, et al.
Publicado: (2011)

Dandy-Walker malformations in a case of partial trisomy 9p (p12.1→pter) due to maternal translocation t(9;12)(p12.1;p13.3)
por: Vundinti, Babu Rao, et al.
Publicado: (2007)

Correlation between the type of bcr-abl transcripts and blood cell counts in chronic myeloid leukemia – a possible influence of mdr1 gene expression
por: Balatzenko, Gueorgui, et al.
Publicado: (2011)

Chromosomal aberrations in hematological malignancies: A guide to the identification of novel oncogenes
por: Vundinti, Babu Rao, et al.
Publicado: (2011)

Incidence of down syndrome: Hypotheses and reality
por: Vundinti, Babu Rao, et al.
Publicado: (2011)

Chromosomal instability and cancer: An insight into the rhythm of life
por: Vundinti, Babu Rao, et al.
Publicado: (2009)

Translocation t(2;14)(p13;q32) in a case of Ph+ acute lymphoblastic leukemia
por: Kerketta, Lily, et al.
Publicado: (2007)

Acceleration of Bcr-Abl(+) leukemia induced by deletion of JAK2
por: Grundschober, E, et al.
Publicado: (2014)

Current and emerging therapeutic strategies for Fanconi anemia
por: Shukla, Pallavi, et al.
Publicado: (2012)

Myeloid/lymphoid neoplasms with eosinophilia/basophilia and ETV6-ABL1 fusion: cell-of-origin and response to tyrosine kinase inhibition
por: Yao, Jinjuan, et al.
Publicado: (2020)

Tryptase Positivity in Chronic Myeloid Leukemia With Marked Basophilia
por: Khafateh, Youssef, et al.
Publicado: (2020)

Marked paraneoplastic basophilia accompanying eosinophilia in a cat with alimentary T-cell lymphoma
por: Balan, Maria, et al.
Publicado: (2017)

FANCA Gene Mutations with 8 Novel Molecular Changes in Indian Fanconi Anemia Patients
por: Solanki, Avani, et al.
Publicado: (2016)

Entire ABL1 Gene Deletion Without BCR/ABL1 Rearrangement in a Female Patient with B-Cell Precursor Acute Lymphoblastic Leukemia
por: Jiang, Yijing, et al.
Publicado: (2020)

BCR‐ABL exon 7 deletion and novel point mutation in patient with chronic myelogenous leukemia and TKI resistance
por: Mikhailov, Ilya
Publicado: (2018)

Allosteric inhibition enhances the efficacy of ABL kinase inhibitors to target unmutated BCR-ABL and BCR-ABL-T315I
por: Mian, Afsar Ali, et al.
Publicado: (2012)

Evaluation of Danazol, Cyclosporine, and Prednisolone as Single Agent or in Combination for Paroxysmal Nocturnal Hemoglobinuria
por: Ghosh, Kanjaksha, et al.
Publicado: (2013)

The Functional Interplay Between the t(9;22)-Associated Fusion Proteins BCR/ABL and ABL/BCR in Philadelphia Chromosome-Positive Acute Lymphatic Leukemia
por: Rafiei, Anahita, et al.
Publicado: (2015)

Philadelphia Chromosome‐positive Chronic Myelogenous Leukemia with Deleted Fusion of BCR and ABL Genes
por: Ohyashiki, Kazuma, et al.
Publicado: (1990)

Targeting BCR-ABL(+) stem/progenitor cells and BCR-ABL-T315I mutant cells by effective inhibition of the BCR-ABL-Tyr177-GRB2 complex
por: Chen, Min, et al.
Publicado: (2017)

Comparative analysis of imaging diagnostic models for tubular basophilia and mineralization of kidney
por: Byun, Jong Su, et al.
Publicado: (2022)

BCR‐ABL exon 7 deletion and novel point mutation in patient with chronic myelogenous leukemia
Publicado: (2019)

BCR/ABL1 and BCR are under the transcriptional control of the MYC oncogene
por: Sharma, Nitesh, et al.
Publicado: (2015)

Pterostilbene downregulates BCR/ABL and induces apoptosis of T315I-mutated BCR/ABL-positive leukemic cells
por: Kawakami, Shohei, et al.
Publicado: (2022)

Pattern of chromosome involvement in childhood hyperdiploid pre-B-cell acute lymhoblastic leukemia cases from India
por: Kerketta, Lily S., et al.
Publicado: (2014)

BCR: a new target in resistance mediated by BCR/ABL-315I?
por: Haberbosch, Isabella, et al.
Publicado: (2016)

Persistence of chronic myelocytic leukemia despite deletion of rearranged bcr/c-abl sequences in blast crisis
Publicado: (1986)

The novel anticancer agent JNJ-26854165 is active in chronic myeloid leukemic cells with unmutated BCR/ABL and T315I mutant BCR/ABL through promoting proteosomal degradation of BCR/ABL proteins
por: You, Liangshun, et al.
Publicado: (2016)

Coexistence of JAK2 and BCR-ABL mutation in patient with myeloproliferative neoplasm
por: Hassan, Abdulaziz, et al.
Publicado: (2015)

Acute Myeloid Leukemia with Concomitant BCR-ABL and NPM1 Mutations
por: Mariotti, Benedetta, et al.
Publicado: (2019)

Relation Between Basophilia and Fine Structure of Cytoplasm in the Fungus Allomyces macrogynus Em
por: Blondel, Benigna, et al.
Publicado: (1960)

Expanding the Diversity of Allosteric Bcr-Abl Inhibitors
por: Deng, Xianming, et al.
Publicado: (2010)

An In-House Method for Molecular Monitoring of BCR-ABL
por: Sercan, Hakkı Ogün, et al.
Publicado: (2012)

Depression of oncogenecity by dephosphorylating and degrading BCR-ABL
por: Gao, Miao, et al.
Publicado: (2016)

BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility
por: Zheng, Xiaomin, et al.
Publicado: (2006)

AHI-1 interacts with BCR-ABL and modulates BCR-ABL transforming activity and imatinib response of CML stem/progenitor cells
por: Zhou, Liang L., et al.
Publicado: (2008)

The HSP90 inhibitor KW-2478 depletes the malignancy of BCR/ABL and overcomes the imatinib-resistance caused by BCR/ABL amplification
por: Zeng, Dachuan, et al.
Publicado: (2022)

Coexistence of p190 BCR/ABL Transcript and CALR 52-bp Deletion in Chronic Myeloid Leukemia Blast Crisis: A Case Report
por: Seghatoleslami, Mohammad, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jbm7e4rfrtnplkhivpl31ln9pr